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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LATS1
All Species:
31.82
Human Site:
Y731
Identified Species:
50
UniProt:
O95835
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95835
NP_004681.1
1130
126870
Y731
K
V
D
T
K
A
L
Y
A
T
K
T
L
R
K
Chimpanzee
Pan troglodytes
XP_001173355
1130
126853
Y731
K
V
D
T
K
A
L
Y
A
T
K
T
L
R
K
Rhesus Macaque
Macaca mulatta
XP_001090321
809
89257
E471
R
K
N
S
R
D
E
E
K
R
E
S
R
I
K
Dog
Lupus familis
XP_534537
1097
121903
Q718
K
D
V
L
N
R
N
Q
V
A
H
V
K
A
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8BYR2
1129
126167
Y730
K
V
D
T
K
A
L
Y
A
T
K
T
L
R
K
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506215
1121
123969
Y721
K
V
D
T
D
A
L
Y
A
T
K
T
L
R
K
Chicken
Gallus gallus
XP_419666
1136
127431
Y737
K
V
D
T
K
A
L
Y
A
T
K
T
L
R
K
Frog
Xenopus laevis
NP_001087838
1118
125984
Y717
K
T
D
T
N
A
L
Y
A
M
K
T
L
R
K
Zebra Danio
Brachydanio rerio
NP_001018346
1068
120780
R707
A
D
N
E
W
V
V
R
L
Y
Y
S
F
Q
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VA38
1105
122470
Y746
I
D
T
S
N
H
L
Y
A
M
K
T
L
R
K
Honey Bee
Apis mellifera
XP_395146
1137
124999
Y767
K
L
D
T
N
Q
F
Y
A
M
K
T
L
R
K
Nematode Worm
Caenorhab. elegans
Q2L6W9
476
55529
I138
H
V
R
A
E
R
D
I
L
S
E
A
D
C
D
Sea Urchin
Strong. purpuratus
XP_795100
1199
133231
Y807
K
V
D
T
N
A
L
Y
A
V
K
K
L
R
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P53894
756
86927
S418
W
V
V
S
L
Y
Y
S
F
Q
D
A
Q
Y
L
Red Bread Mold
Neurospora crassa
P38679
598
67999
R260
K
D
Q
L
A
H
V
R
A
E
R
D
I
L
A
Conservation
Percent
Protein Identity:
100
99.6
35.8
50.9
N.A.
92.8
N.A.
N.A.
80.8
85.2
74.7
63.1
N.A.
38.6
40.2
20.7
38
Protein Similarity:
100
99.8
44.7
63.4
N.A.
96.7
N.A.
N.A.
87.1
92.1
83.4
73.7
N.A.
50.2
52.6
29.6
51.9
P-Site Identity:
100
100
6.6
6.6
N.A.
100
N.A.
N.A.
93.3
100
80
0
N.A.
53.3
66.6
6.6
80
P-Site Similarity:
100
100
46.6
13.3
N.A.
100
N.A.
N.A.
93.3
100
80
26.6
N.A.
60
73.3
26.6
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
28
24.4
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
42.3
35.5
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
7
7
47
0
0
67
7
0
14
0
7
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% C
% Asp:
0
27
54
0
7
7
7
0
0
0
7
7
7
0
14
% D
% Glu:
0
0
0
7
7
0
7
7
0
7
14
0
0
0
7
% E
% Phe:
0
0
0
0
0
0
7
0
7
0
0
0
7
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
7
0
0
0
0
14
0
0
0
0
7
0
0
0
0
% H
% Ile:
7
0
0
0
0
0
0
7
0
0
0
0
7
7
0
% I
% Lys:
67
7
0
0
27
0
0
0
7
0
60
7
7
0
67
% K
% Leu:
0
7
0
14
7
0
54
0
14
0
0
0
60
7
7
% L
% Met:
0
0
0
0
0
0
0
0
0
20
0
0
0
0
0
% M
% Asn:
0
0
14
0
34
0
7
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
7
0
0
7
0
7
0
7
0
0
7
7
0
% Q
% Arg:
7
0
7
0
7
14
0
14
0
7
7
0
7
60
0
% R
% Ser:
0
0
0
20
0
0
0
7
0
7
0
14
0
0
0
% S
% Thr:
0
7
7
54
0
0
0
0
0
34
0
54
0
0
0
% T
% Val:
0
54
14
0
0
7
14
0
7
7
0
7
0
0
0
% V
% Trp:
7
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
7
7
60
0
7
7
0
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _